SORD anticorps (AA 211-239)
Aperçu rapide pour SORD anticorps (AA 211-239) (ABIN5532181)
Antigène
Voir toutes SORD AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 211-239
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This SORD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-239 amino acids from the Central region of human SORD.
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Isotype
- Ig Fraction
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Indications d'application
- For WB starting dilution is: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SORD (Sorbitol Dehydrogenase (SORD))
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Autre désignation
- SORD
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Sujet
- Sorbitol dehydrogenase (SORD, EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1, MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.
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Poids moléculaire
- 38 kDa
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ID gène
- 6652
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UniProt
- Q00796
Antigène
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